diff options
| -rw-r--r-- | gnu/packages/bioconductor.scm | 29 |
1 files changed, 17 insertions, 12 deletions
diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm index b492214971..1401053570 100644 --- a/gnu/packages/bioconductor.scm +++ b/gnu/packages/bioconductor.scm @@ -13791,20 +13791,25 @@ relevant, and the minimum expression of the most abundant condition.") r-summarizedexperiment)) (native-inputs (list r-knitr)) - (home-page - "https://github.com/HelenaLC/CATALYST") + (home-page "https://github.com/HelenaLC/CATALYST") (synopsis "Cytometry data analysis tools") (description - "This package is Cytometry dATa anALYSis Tools (CATALYST). Mass -cytometry (CyTOF) uses heavy metal isotopes rather than fluorescent tags as -reporters to label antibodies, thereby substantially decreasing spectral -overlap and allowing for examination of over 50 parameters at the single cell -level. While spectral overlap is significantly less pronounced in CyTOF than -flow cytometry, spillover due to detection sensitivity, isotopic impurities, -and oxide formation can impede data interpretability. We designed -CATALYST (Cytometry dATa anALYSis Tools) to provide a pipeline for -preprocessing of cytometry data, including i) normalization using bead -standards, ii) single-cell deconvolution, and iii) bead-based compensation.") + "This package is @dfn{Cytometry dATa anALYSis Tools} (CATALYST). Mass +cytometry like @dfn{Cytometry by time of flight} (CyTOF) uses heavy metal +isotopes rather than fluorescent tags as reporters to label antibodies, +thereby substantially decreasing spectral overlap and allowing for examination +of over 50 parameters at the single cell level. While spectral overlap is +significantly less pronounced in CyTOF than flow cytometry, spillover due to +detection sensitivity, isotopic impurities, and oxide formation can impede +data interpretability. @code{CATALYST} was designed to provide a pipeline for +preprocessing of cytometry data, including: + +@enumerate +@item normalization using bead standards; +@item single-cell deconvolution; +@item bead-based compensation. +@end enumerate +") (license license:gpl2+))) (define-public r-erma |