From a8631c816d78ede76f279e288efbb284090f8c91 Mon Sep 17 00:00:00 2001 From: Mădălin Ionel Patrașcu Date: Sun, 30 Oct 2022 01:16:05 +0200 Subject: gnu: Add r-decomplexdisease. * gnu/packages/bioconductor.scm (r-decomplexdisease): New variable. --- gnu/packages/bioconductor.scm | 33 +++++++++++++++++++++++++++++++++ 1 file changed, 33 insertions(+) diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm index e25c4d0e95..e4c8d9cdb5 100644 --- a/gnu/packages/bioconductor.scm +++ b/gnu/packages/bioconductor.scm @@ -3220,6 +3220,39 @@ reveals feature associations to hidden subclasses not exclusively related to higher deregulation levels.") (license license:gpl3+))) +(define-public r-decomplexdisease + (package + (name "r-decomplexdisease") + (version "1.16.0") + (source (origin + (method url-fetch) + (uri (bioconductor-uri "DEComplexDisease" version)) + (sha256 + (base32 + "09a967x1rnv7byjwh29ngjhs67rgg27zblmlzx6pyqlwy5jsp89d")))) + (properties `((upstream-name . "DEComplexDisease"))) + (build-system r-build-system) + (propagated-inputs + (list r-biocparallel + r-complexheatmap + r-deseq2 + r-edger + r-rcpp + r-summarizedexperiment)) + (native-inputs (list r-knitr)) + (home-page "https://bioconductor.org/packages/DEComplexDisease") + (synopsis "Investigations of complex diseases by bi-clustering analysis") + (description + "DEComplexDisease is designed to find the @acronym{DEGs, Differential +Expressed Genes} for complex disease, which is characterized by the +heterogeneous genomic expression profiles. Different from the established DEG +analysis tools, it does not assume the patients of complex diseases to share +the common DEGs. By applying a bi-clustering algorithm, DEComplexDisease +finds the DEGs shared by as many patients. Applying the DEComplexDisease +analysis results, users are possible to find the patients affected by the same +mechanism based on the shared signatures.") + (license license:gpl3))) + (define-public r-deconvr (package (name "r-deconvr") -- cgit v1.2.3